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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501aef5b8e3f487d4cbe3eda84f8330dbeb7c9f452c7893c5bea50ff5dd7d3e4' 
  AND token = 'uGBz/zJXDYfdwS2LkfDJynk+HZvKCa45wPdGE9K3U6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}