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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '620fec264ba5a7b3c1cb1ee1a260a827db4bd00244a0fde85376c0dc096f3011' 
  AND token = 'i0cRyN4SUkid6O+mAB8XWzQA0ZFMw/zj3mlYyJDwGIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}