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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b2edb37ee46fba962b8c322365bd0bc41abe3162bee7f52398cfe8bb45f9f6' 
  AND token = '49YTL4dmuVufs/s6+XnrjGvPNgA+9XA47bmPPcXJJyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}