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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817eb7a1bd8d197e09a01406985289b0441875e8f50fbbde45b2821b16c562ec' 
  AND token = '1V/l1EMXdqdBaTNTlvhw2UaNi8/Ie7sF/XFap49QwiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}