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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0432d26c867fa57ad9387cd1221677991fa985d063315f36c11979a64e33d0af' 
  AND token = 'ATkGgRisJatLH1f/uEGYDCDt2nj2YFAUEb/+B9LEDzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}