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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c758a8639210c1e8a6c3d5034391ed64e0d4c106433d083adb0b16869cba3021' 
  AND token = 'oz5MHC54emzWM/QwtPG595nDw5bCFannrzCEAwr8ZTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}