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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '876c4d42ab18cfbab409bd3c7e09341d6781b1355f59f266a3668ac18cb18ec0' 
  AND token = '+59ETtp9V5pHp/p+yLWCN1nw5T6zt8bx/4ouR97tspo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}