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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d06ddbb0e7a112af0ddc8cf20a25e3671a7857d4f064fdaf1649ce92771a75' 
  AND token = 'RWsVVdgh5/UxI1wD3ZVMb3PJlm8DRmE6zuEjNA/0p9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}