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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b356b10d6ad08d2f80e534cfa7f0bed11aebd12ef5018a421d06450b930b2f70' 
  AND token = '5bqLNZDihdY2Pl2EmWwoyDAX310je9G2OCfU6onlStE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}