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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de66a9688779e7f126fe72c919f4aca78488241a827de0e37e45cd14d4a3ca43' 
  AND token = '+pMoVcGRNYjQUjGvYEv59YGtJdRxjC2CcREEdCFVGM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}