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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0d3226a1c76c111968d4a5c11e5fd07cea633377c3136ab85163ad9becf5a5' 
  AND token = '8W1x/luYqUNGg44TxKijP3c6GvWtGreUS0DfQTCZOgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}