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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8e18c1b7b62e81edb489dca269e8295a3579d4dac78ff71d72e1a4220991be' 
  AND token = 'ESGBYNUmbQQc2VSWdaWeszl/GfNpz73GL3LVU8w4hko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}