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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229f47290752d488f461057b58a7918f06dc7cd9e40096eec0d49c8b76f4c188' 
  AND token = 'XpFUQYmX3gs7WRF5DbT36JVfmW1KI0FrlHQsIqrx+nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}