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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2562f52ecd061345ad829f6ea3eb5de7f2142a9f4f63472555f12e6c6829c29' 
  AND token = 'QS5s0mmORwEC1MvhhxR33+PId50gDxMkvP+/9BtR8is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}