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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9d4d9a4b9ee3894dd5f007ee4921fa54c1c2f0a8fdc749773e01211507c1b57' 
  AND token = 'vm/905wAjI8KB0eEQbp3EuTcCup+IST9KRc/bn6m5Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}