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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c35a1e3436ef24184c372b2ad4f364d49e3d860ea7a95b8d7822a4c160cdf8' 
  AND token = 'Ec9YI87VdpN+Ts4Ffya1bsu6vV9N6MRMADUACmbvu7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}