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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74ef20c3cd58917dc79fe63bb6a3b9e7037df0abc19472825a47999d1f635744' 
  AND token = 'qoBKA/tDlBxBunolXoiXjI8X2oUdRrrcMHUq2BcPHtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}