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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e348700185149fd1afa11d1f4a48446c0b71757eb5d76f177e4ddba65b769b' 
  AND token = 'pfEFmsufOyoVuqVwNR8DKWffBZTnA5sruMn0TAoZxr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}