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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5dc47843e76affe8451fd582b55f49ca125553b922fef4c065808f220b0df0e' 
  AND token = 'sFlR5Gp0v0qCp2wP2dDDWeI4wc72iO5tQL693D9SmCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}