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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df5dfafede8d3c62e7c9251b124a9988ba004694bc3482f4384f4019029bee8' 
  AND token = 'pfPZ7qs2y16eIaRinbPmOXTiW8D6d+8skbwAngGtwDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}