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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3580b77a8b582eab333d98975782c22a2defa89c8993fc754bceec6e73c30abd' 
  AND token = '6oAGerA5M/+fiQNWfbKKi65eAqT3wWu1ftuqI9mT/cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}