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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86156c6a3794857f010574e92cd660fc196e12268c07e2e667894b28e65a69f6' 
  AND token = 'FaBHURODNWfhghDMgi2C1kZOXuUnqLKZ8h75FFiUhTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}