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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a1f661d3903fc183d5fafbeea2eb3546d61134e45475f40403208dbcf52b2a' 
  AND token = 'lrFdSVpYC0Sak2FVffIJyhh3juP/14XaGUSRoyQUWGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}