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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07ef114485b58fa02e5dc2df40fef89a8fdf4d7ff72bfb03d9db78d9506e212' 
  AND token = 'jCfXaG4nJo7JPBpItkE5Igx+QCzEfSlao4ldXc7Wwlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}