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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6786305b2bcfee7903b01b52b79033f8a200a644e69ea83cc2532648a6c8b7be' 
  AND token = 'AG9LVglPGvJuDwXBpp8ypCY+cP6nf6U2qA6nFoFk0xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}