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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9970cac8aea410a13713696bb8a3fa44debdd8b49b36affa421e70507afb655f' 
  AND token = '722v+bqDlsslRqLG381NdldSOk4dVuGkNlVOX5gnmgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}