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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2f42b1490f7eb4a03c374a5c55eb5ee54e8e1d02fc8f5496464d549c0c3280' 
  AND token = 'opJ/dYBDyksDPfi+Kwu/HeXibiWgMSSFJSDPwH6WuMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}