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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ae57080dfdf76c52c2e8a0e6e0a350d7f3f283bec510fa477ec2d95c260bb1' 
  AND token = 'VJAMCu8dZ2mZtd3YiL/Oxli9zi56xlo+wR2PpFSsTFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}