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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f303e949fbdadd9c5e2cf760b123289c2700803e4c8493beb45270f5b5a2218' 
  AND token = 'owSSUC3NNC/G+C1gEv1o6JQvV4HAzMrpsS7IXyRPtmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}