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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1f275b63fbe5dcb74828a96a38bce9d82d48ac5185d7224065f50e0b9e7a58d' 
  AND token = 'dczK5dX1U8QPRdiJcVOChErMUlVg+pPrpbgZOqzkZ2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}