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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '231b91df52f4f3f1ec389b43d22f6a0fe517f5ef36fccc176b489ca2f08bd3c2' 
  AND token = 'vyIvuXbwS4GJtpaKC7HUvs8sJg2lYtteASWpgh8ZEN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}