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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6765f98d8fe02776ab1b71066d872140b7f0fd21666abae2d067e960bff2a2e9' 
  AND token = 'w0nWHJAHiUBCj6Wl+FpdwtDUiqFI4QXG9JGMazIoYzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}