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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544cf123347b5c219d62dd72d1d3a9835a9bff73aac9a8efe95549f54040be70' 
  AND token = 'tSrs5SbJ4+NEm24/xwbR+ezUvVClb7N7pGjajV9KAD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}