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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be449ab3fccd0453feffbdb5d494ed029c597b41607f9ab9b2464b0f4e2c60c' 
  AND token = '5EHg1pv/aBaYcE1V+a2cgEEsCZHjDD4qL/0s653i1hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}