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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5beddce1557199b8f72cb31c2b0c5c588e5a8218cdb175765753f8067b61cf0' 
  AND token = 'IXbW7eVXLSUwZ92G3LcUUiUXuUixm0cKQ2KTCW+IOeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}