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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e1205f49a8098137ce3a6792b1b69adf7d558e15ba5fa9f28f629504519435' 
  AND token = 'byAhxrxwp28W09UTTPnF+lNbD0EBmH16TgrkEu5pGYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}