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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33386330a3d2fce774b29826cc9ddc7f148e6651ef26b95a794769ebf3a8155e' 
  AND token = '8B0u6PWpdJ3ObDm0MI2PNdHnRWFph4rfcyzRgjkYWSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00181

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}