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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dda60974f8e0e6815695345f32b5a6eca9fc9e1e2e031fb30a78fe9d9693b356' 
  AND token = 'Dq1vElg+kd6h16pNLXigC6sQRdyXvpKcOYPmRZaBf1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}