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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376f0c8818d705b4ceed22e75da7b72c4ce616205d172b144ced4a4d02962c7c' 
  AND token = '735j3e6f48JTm/zZo95e/E1H8OTbOJi4WRxpXOGhyGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}