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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd342225723a4919670b52e6649b3e90945323c924f13b691de069b17930ffaed' 
  AND token = 'N/EJtYGiBurE4bpmwz9rXj7G5kTb+GFuHGCbl+dwomc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}