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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1837f5337e0c1064c547940b213cd3d07cdca4c18ecc7e93dfeddde5a9eb264a' 
  AND token = 'nBxVshap+v3e6Ue2HwBAqcwXrNKy1hYfjm8mGxCIBQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}