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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80416ce085f7c3fdfb0a269660be9e55eebf1eac01f2965de432a6c58c2970c' 
  AND token = '2GbPJxVDHsrkHkwCGQrDT6OM4GUs1EKvAxMOCcqjz2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}