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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b9688cfcf485f6303b2735e3dbea0fd2a3b2c8aa1a6745f8c3b8c415b71c1e' 
  AND token = 'LNBYCH/xBYHnPsXjkxnLk7M9Zjv1ok2VYcxfeHYf+CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}