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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b43c09207120cc53183c562646c3910d084c8082f667bdd6b2836c2968a21bc' 
  AND token = 'xmg9Plt69GRhyZW/F2AOCV6B+NUyiUj4L9i/o5+1VI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}