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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a68aaf803b8b52ac0d82e12f442a657c609cbb85924150c2b456f44c8ffb85' 
  AND token = 'IHFI4gEtb6SgTAgzMuf5od5b8y9M4TEh8CiRmLjIOwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}