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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6eca14335b218cd0612028302852ae0a3639dd66f45b1354045a62b6d0e828' 
  AND token = 'CTk1N81ca06SaNZ/DyeivqtZA8GtUGvIMcjHmTrlrBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}