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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '511ee8e25f47dfaadd88f8a97445b9e8e5e5d9342a666b7356c1f1fd78c1f3ba' 
  AND token = 'MP2ufE+W5iUdiit0uuCP30credTPG///2UY8vj2hi8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}