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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e9ef9a6747a0c5d760e457c0c9811e4cade53aba4bb2b77e5ea6acd3d23110' 
  AND token = 'ZdUmOmaPAVmCM2h/43xjenWba7DYVIAl61aSgBphfh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}