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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6bd4067e3b8d5ab8baca1f248b90b8f756c5c7fc19b67e33c4b1ae21b475812' 
  AND token = 'Ztw/QxRM9oS76uAW8vTp3vkZgm2e372+BlKQM/BV4NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}