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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ef12951767a5862b504c42b9a3ec7f3223576f505c492fd6001d67d5be0cb35' 
  AND token = 'b9j9nT9AN3NqqqRIdZaytAKaMvAxLDiWd0s6SDijkwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}